For those who have heard it, this is an insanely gloomy song. I've listened to it three times and it gives me the creeps just thinking about it.
Now, as any Alice In Chains fan would know, Layne Staley died from drug overdose, giving people the thought that most of his lyrics came from his struggle with his addiction. However, I believe this is a different case. Lyrics in the beginning suggest that he, the person who is supposedly singing the song, was betrayed by a person who he considered a friend.
The chorus is simply "Why does it have to be?" over and over, suggesting the person is coping over himslf being betrayed.
The second verse seems to talk about a child who is a very innocent child who is introduced to some form of pain, possibly some form of abuse or maybe being lately introduced to the "real world", followed by the chorus.
Now the ending is very interesting. It appears he is talking to himself about, well, I couldn't tell you. "They never gonna fu*k with me again" possibly implies that he wants to commit suicide, although "I'm still young" implies that he has an internal conflict. "I just want to go straight through you... make your eyes dialate...Irate" Can also imply he wants to kill someone he is mad at angrily. However, with many randomly placed terms throughout the song it is really dufficult to understand exactly what it is about.